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test is not perfect

To sum up, this test is not perfect, as it is prone to ‘false positive’ and ‘false negative’ test results. A false positive test (high level of PSA in the absence of cancer) is usually followed by other diagnostic tests, which can not only be costly, but can carry certain potential risks for the individual as well. On the other hand, false negative results may show the PSA to be in the normal range, even when the cancer is actually present..

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